Transplant: Strongyloidiasis Table 2

Table 2. Summary of treatment for Strongyloides infection

Syndrome	First Line Therapy	Second Line Therapy	Follow-up	Notes
Chronic Intestinal Strongyloidiasis	Ivermectin 200 mcg/kg PO daily x2 days, repeat at 2 weeks	Albendazole 400 mg or Thiabendazole 25 mg/kg PO twice daily x3 days, repeat at 2 weeks	Repeat stool screening to verify clearance	Immunocompromised patients may require longer course of therapy and/or suppression
Strongyloides Hyperinfection Syndrome / Disseminated Infection	Ivermectin 200 mcg/kg PO twice daily until larval clearance documented from all affected sites, repeat at 2 weeks.	Albendazole 400 mg PO twice daily or Thiabendazole 25 mg/kg PO BID until larval clearance documented from all affected sites, repeat at 2 weeks.	Repeat stool screening to verify clearance and monitor for relapse.	Ivermectin administration by alternative routes has been attempted (see table 2). Consider combination therapy.